At which gestational weeks is anti-D immunoglobulin administered?

Anti-D immunoglobulin is typically administered to Rh-negative pregnant women at 28 weeks and again at 34 weeks of gestation. This timing is crucial because it helps prevent Rh sensitization, which can occur if an Rh-negative mother carries an Rh-positive fetus. Sensitization can lead to hemolytic disease of the newborn in future pregnancies, making the administration of anti-D immunoglobulin at these gestational ages a vital preventive measure.

Administering the immunoglobulin at 28 weeks allows for the effective prevention of sensitization during the latter part of the pregnancy. The second dose at 34 weeks ensures continued protection up to the point of delivery, since any potential exposure to Rh-positive blood can be addressed before labor. This regimen aligns with current clinical guidelines and practice to safeguard both maternal and fetal health.

Other suggested choices either represent incorrect timing for immunoglobulin administration or do not follow the recommended guidelines established in obstetric care.