What is a surprising risk factor associated with corrected undescended testes?

The association between corrected undescended testes and an increased risk of testicular cancer is well established in the medical literature. Males with a history of cryptorchidism, even after surgical correction through orchidopexy, have been shown to have a significantly higher risk of developing testicular tumors compared to those with normal testicular descent. This is believed to be due to a combination of factors including hormonal abnormalities, changes in the testicular microenvironment, and possibly genetic predispositions that influence both the undescended condition and the risk of oncogenesis.

Crucially, while surgical correction may improve fertility outcomes and testosterone levels, the underlying risk remains elevated for testicular cancer, making surveillance and awareness vital for those affected. Therefore, the assertion that this condition contributes to a heightened risk of cancer aligns with current research findings and clinical recommendations for follow-up in these patients.