What is the first-line treatment for uncomplicated chlamydia?

The first-line treatment for uncomplicated chlamydia is azithromycin, which is administered orally as a single dose of 1 gram. This treatment is preferred because it is effective and offers the advantage of convenient single-dose therapy, which promotes adherence.

Doxycycline, while effective and an alternative treatment option, is not typically the first choice for uncomplicated chlamydia due to the longer duration of therapy required—100 mg twice daily for 7 days. This can impact patient compliance compared to a single dose regimen.

Metronidazole is primarily used for bacterial vaginosis and trichomoniasis but is not effective against chlamydia.

Ciprofloxacin, although an antibiotic, is not commonly used as first-line therapy for chlamydia and is usually reserved for other types of infections.

In summary, azithromycin's single-dose administration and efficacy make it the most recommended first-line treatment for uncomplicated chlamydia.