What is the recommended vaccination schedule for Shingrix in adults aged 65?

The recommended vaccination schedule for Shingrix, which is a vaccine for the prevention of shingles, includes administering two doses to adults aged 65 and older. The first dose is given at a designated starting point, referred to as "0," and the second dose is administered between 2 to 6 months later. This two-dose schedule is effective in establishing a strong immune response against the varicella-zoster virus, which causes shingles.

This approach contrasts with some other vaccination protocols for certain conditions that may require only a single dose or a different number of doses. For instance, Shingrix’s two-dose regimen is specifically designed to enhance immunogenicity and durability of protection in older adults, a population that is at higher risk for severe complications from shingles.

The other potential options do not align with the established guidelines for Shingrix. A single dose would not provide adequate protection, while three doses are not recommended for this vaccine in adults, and an annual vaccination is unnecessary for Shingrix, as the vaccine is intended for long-lasting immunity. Adhering to the two-dose schedule is vital for effective prevention of shingles and its associated complications.