Which medication is commonly used for chronic non-cancer pain management?

Gabapentinoids, such as gabapentin, are widely used in the management of chronic non-cancer pain due to their unique mechanism of action and efficacy in treating specific types of pain, particularly neuropathic pain. These medications work by modulating neurotransmitter release and inhibiting excitatory pathways in the central nervous system, which can help reduce the perception of pain.

Chronic non-cancer pain can arise from various sources, including nerve damage, injury, or conditions like fibromyalgia and diabetic neuropathy. Gabapentinoids have been shown in numerous studies to provide significant pain relief in these conditions, making them a preferred choice among clinicians when addressing chronic pain syndromes.

In addition to their pain-relieving properties, gabapentinoids are often well-tolerated compared to other classes of analgesics, with a lower risk of dependency or abuse, particularly in comparison to opioids. This makes them especially valuable in managing chronic pain without the associated risks that come with long-term opioid therapy.

Other options, while they may have roles in pain management, are not as commonly used specifically for chronic non-cancer pain as gabapentinoids are. For instance, paracetamol is often used for mild pain but may not provide adequate relief for