Which of the following is NOT a situation indicating a high risk for BRCA1/2 mutation?

A situation indicating a high risk for BRCA1/2 mutations typically involves family histories that suggest a genetic predisposition to breast and ovarian cancers. The presence of multiple cases of breast cancer within the same side of the family, particularly among first-degree relatives, is a significant indicator. Similarly, having male relatives with breast cancer also raises concern as males with BRCA mutations can develop breast cancer, which is notably rare and thus suggested strong genetic links.

In contrast, having only one first-degree relative with breast cancer does not generally elevate the risk for BRCA1/2 mutations to the same extent as the other scenarios. The threshold for genetic testing, particularly concerning BRCA1/2, often considers more substantial family history or multiple cases of breast cancer, indicating that a single case, while still concerning, does not equate to a high-risk scenario alone. Therefore, this situation does not warrant the same level of genetic concern as the other options listed, making it the correct choice for being not indicative of high risk for BRCA1/2 mutation.