Which SGLT2 inhibitor is known for being effective in managing diabetes?

Prepare for the Royal Australian College of General Practitioners exam with interactive quizzes, flashcards, and multiple-choice questions. Learn with detailed explanations and ace your exam!

Empagliflozin is an SGLT2 inhibitor that has shown significant effectiveness in managing type 2 diabetes. SGLT2 inhibitors work by preventing the reabsorption of glucose in the kidneys, leading to increased glucose excretion through urine and thereby helping to lower blood sugar levels.

Empagliflozin has also demonstrated cardiovascular benefits, which adds to its importance in the management of diabetic patients, particularly those who are at risk for cardiovascular events. This dual benefit makes it a valuable option in diabetes management protocols.

In contrast, the other medications listed belong to different classes of diabetes medications. Semaglutide is a GLP-1 receptor agonist, while gliclazide is a sulfonylurea that stimulates insulin secretion from the pancreas. Sitagliptin is a DPP-4 inhibitor that works by prolonging the action of incretin hormones, which help regulate insulin and blood sugar levels. While these medications are effective in their own right, they do not function as SGLT2 inhibitors like empagliflozin.

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